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Table 2 Summary of outcomes with significant results

From: Involving community pharmacists in interprofessional collaboration in primary care: a systematic review

 

Outcome criteria

Intervention vs. control group

Difference in change between Intervention and Control group

P value

Carter B. (2009) [25]

Proportion of patients with BP control at 6 months (%)

63.9 vs. 29.9 (OR 3.2, 95% CI 2.0-5.1)

-

p < 0.001

Proportion of patients with BP control without diabetes mellitus at 6 months (%)

68.8 vs. 32.4 (OR 3.9, 95% CI 3.1-5.0)

-

p < 0.001

Proportion of patients with BP control with diabetes mellitus at 6 months (%)

45.5 vs. 26.1 (OR 4.7, 95% CI 1.7–13.1)

-

p = 0.003

SBP at 6 months (mmHg)

-20.7 vs. -6.8

-

p < 0.05

Carter B. (2015) [26]

SBP at 9 months (mmHg)

131.6 vs. 138.2

-6.1 (95% CI-9.75 to -2.39) *

p = 0.002

DBP at 9 months (mmHg)

76.3 vs. 78.0

-2.9 (95% CI -4.85 to -0.93) *

p = 0.005

SBP in minority ethnicity subjects at 9 months (mmHg)

133.0 vs. 140.3

-6.4 (95% CI -11.16 to -1.68) *

p = 0.009

DBP in minority ethnicity subjects at 9 months (mmHg)

77.9 vs. 78.8

-2.9 (95% CI -5.88 to -0.08) *

p = 0.044

Carter B. (2018) [27]

Proportion of patients with Body Mass Index screening and follow-up at 12 months (%)

68.0 vs. 37.4

-

p < 0.001

Proportion of patients with alcohol use screening at 12 months (%)

98.0 vs. 88.2

-

p < 0.001

Chen Z. (2013) [28]

24-hour SBP at 6 months (mmHg)

120.4 vs. 131.8

-

p < 0.001

Proportion of patients with BP control at 6 months (%)

75.6 vs. 50.0

-

p < 0.001

Finley P. (2002) [39]

6-months Medication Possession ratio (MPR)

0.811 vs. 0.659

-

p < 0.005

Patient satisfaction survey results at 6 months

Patients in intervention group were more likely to have received an antidepressant previously: 25.0% vs. 19.0%

-

p = 0.044

Finley P. (2003) [40]

Patient satisfaction survey results at 6 months

Patients in the intervention group expressed greater satisfaction than did control group with the personal nature of care, availability of providers, ability of providers to listen, explanation of why antidepressants were prescribed, explanation of how to take the antidepressants and patient’s overall satisfaction with the health maintenance organization

-

p < 0.05

Hogg W. (2009) [30]

Number of patients with influenza vaccination

-

0.087 (95% CI 0.012–0.162) **

p = 0.023

Number of patients with screening for colorectal cancer

-

0.167 (95% CI 0.046–0.288) **

p = 0.0070

Number of patients with hearing examination

-

0.273 (95% CI 0.106–0.44) **

p = 0.0016

Number of patients with eye examination

-

0.220 (95% CI 0.076–0.364) **

p = 0.0029

Jameson J. (2010) [31]

HbA1c for male patients at 12 months (%)

-1.90 vs. -0.15

-

p = 0.03

Proportion of patients who achieved at least a 1.0% decrease in HbA1c at 12 months (%)

67.3 vs. 41.2

-

p = 0.02

Proportion of patients who achieved at least a 1.0% decrease in HbA1c for patients of nonwhite race/ethnicity at 12 months (%)

56.3 vs. 22.7

-

p = 0.03

Proportion of patients who achieved at least a 1.0% decrease in HbA1c for male patients at 12 months (%)

72.0 vs. 28.0

-

p = 0.002

Pape G. (2011) [33]

LDL-C at 24 months (mg/dl)

83.0 vs. 95.0

-

p < 0.001

Proportion of patients with LDL-C at target goal at 24 months (%)

78.0 vs. 50.0

-

p = 0.003

Proportion of patients with LDL-C at target if they were not at goal baseline at 24 months (%)

74.0 vs. 48.0

-

p = 0.001

Proportion of patients with LDL-C test within the past 12 months at 24 months (%)

95.0 vs. 82.0

-

p = 0.04

Simpson S. (2011) [34]

Proportion of patients with diminution of 10.0% of SBP at 12 months (%)

37.0 vs. 23.0 (OR 1.91, 95% CI 1.11–3.28)

-

p = 0.02

Proportion of patients with elevated blood pressure at baseline with diminution of 10.0% of SBP at 12 months (%)

50.0 vs. 28.0 (OR 2.55, 95% CI 1.30–5.01)

-

p = 0.007

SBP at 12 months (mmHg)

-7.4 vs. -2.5

-4.9 (95% CI -8.7 to -1.0) *

p = 0.002

DBP at 12 months (mmHg)

-2.3 vs. 0.6

-2.9 (95% CI -5.6 to -0.2) *

p < 0.05

SBP for patients with elevated blood pressure at 12 months (mmHg)

-13.9 vs. -6.7

-

p = 0.002

Predicted 10-year risk of cardiovascular events at 12 months (%)

-2.7 vs. -1.2

-1.5 (95% CI -0.2 to 3.3) *

p = 0.005

Smith S. (2016) [35]

SBP at 9 months (mmHg)

132 ± 16 vs. 141 ± 20

-6.62 (95% CI -12.8 to -0.44) *

p = 0.036

Proportion of patients with an improvement from low to high medication adherence minority ethnicity subjects (antihypertensive use) at 9 months (%)

8.1 vs. 0.0

-

p = 0.016

Tahaineh L. (2011) [36]

Proportion of patients reached their LDL-C goal at 6 months (%)

94.5 vs. 71.2

-

p < 0.001

Proportion of patients reached their total cholesterol goal at 6 months (%)

87.7 vs. 73.1

-

p = 0.038

Proportion of patients reached their HDL-C goal at 6 months (%)

28.8 vs. 50.0

-

p = 0.016

Tobari H. (2010) [37]

DBP at home at 6 months (mmHg)

-3.3 (-4.8 to -1.8) vs. -1.4 (-2.9 to 0.1)

-2.8 (95% CI -5.5 to -0.1) *

p = 0.04

Body Mass Index at 6 months (kg/m²)

-0.4 (-0.7 to -0.2) vs. 0.0 (-0.2 to 0.2)

-0.4 (95% CI -0.7 to -0.1) *

p = 0.008

Sodium reduction score at 6 months

1.3 (0.9 to 1.7) vs. 0.0 (-0.4 to 0.4)

1.2 (95% CI 0.5-2.0) **

p = 0.002

Number of smokers at 6 months

9.0 [14.0] vs. 19.0 [30.0]

0.4 (95% CI 0.2–0.9) **

p = 0.04

Weber C. (2010) [38]

Change in 24-hour SBP at 9 months (mmHg)

136.0 to 130.5 vs. 135.5 to 121.4

-

p < 0.001

Change in 24-hour DBP at 9 months (mmHg)

76.6 to 73.7 vs. 76.0 to 69.2

-

p < 0.001

  1. Abbreviations: BP, blood pressure; DBP, diastolic blood pressure; HbA1c, glycosylated hemoglobin; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure
  2. Legend: Bold text:primary outcomes of study;*Negative values indicate Intervention Group has larger change; **Positive values indicate Intervention Group has larger change